Human mesenchymal stem cell treatment
of premature ovarian failure: new
challenges and opportunities

stem cells premature ovarian failure

Premature ovarian failure (POF) is a common endocrine disease causing female infertility. It is characterized by high gonadotropin expression [follicle-stimulating hormone (FSH) ≥ 40 mIU/mL], low estradiol (E2) expression, and follicular dysplasia in women aged less than 40 years [1].

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